The mammalian target for rapamycin (mTOR) is a serine/threonine-dependent kinase, which plays an essential role in cell expansion, cell proliferation, and protein-synthesizing.
The mTOR pathway regulates phosphoinositide 3 kinase the Akt/PKB signaling pathway, which results in the phosphorylation of 4EBP1 and the beginning of the translation of mRNA. You can know more about Anti-MTOR/mTOR Antibody Picoband online.
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Another pathway is controlling ribosomal kinase that affects the biogenesis of ribosomes and the elongation of translation. Genetic mutations that affect the gene result in the Smith-Kingsmore syndrome.
The mTOR Antibody (30) is a top-grade monoclonal mTOR antigen (also called FRAP1 antibody or FRAP2 antibody, or mechanistic targeting of rapamycin Kinase antibody) that is suitable for the identification that the mTOR protein from mouse, rat, and human origin.
MTOR Antibody (30) can be purchased in the unconjugated anti-mTOR antibody version, and also different conjugated forms of anti-mTOR antibodies, such as HRP, agarose. MTOR also referred to as FRAP is a protein that autophosphorylated serine and connects to FKBP and rapamycin.
mTOR can also be an upstream regulator for S6 kinase. It has also been involved with the control of p27 as well as the expression of p21. MTOR autophosphorylates at Ser2481 under conditions that inhibit translation. The phosphorylation of mTOR at Ser2448 is controlled by the p70S6 kinase.